Executive summary
Approaches used by others and existing safety frameworks
The framework
Categories of scientific evidence : human information and data
Categories of scientific evidence : animal data
Categories of scientific evidence : information about related substances
Categories of scientific evidence : in vitro data
Interactions
Vulnerable groups and prevalence of use
Scientific principles for integrating and evaluating the available data
Applying the framework
Factors influencing use of the safety framework
Findings and recommendations.
Dietary supplements : a framework for evaluating safety. ISBN 0309091101. Published by National Academies in 2005. Publication and catalogue information, links to buy online and reader comments.