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Antibiotics : actions, origins, resistance
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Antibiotics : actions, origins, resistance

Christopher Walsh

Publication Data

Contents

Antibiotics : initial concepts
Introduction to major antibiotic classes and modes of action
Antibiotics that act on cell wall biosynthesis
Antibiotics that block bacterial protein biosynthesis
Antibiotics that block DNA replication and repair : the Quinolones
Other targets of antibacterial drugs
Natural and producer immunity versus acquired resistance
Enzymatic destruction or modification of the antibiotic by resistant bacteria
Antibiotic resistance by efflux pumps
Antibiotic resistance by replacement or modification of the antibiotic target
Regulation of antibiotic biosynthesis in producer organisms
Polyketide antibiotic biosynthesis : assembly line enzymology
Enzymatic assembly lines for nonribosomal peptide antibiotics
Biosynthesis of other classes of antibiotics
New looks at targets
New molecules
Contexts and challenges for the use of new antibiotics.

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Antibiotics : actions, origins, resistance by Christopher Walsh. ISBN 1555812546. Published by ASM Press in 2003. Publication and catalogue information, links to buy online and reader comments.

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