Introduction to biopharmaceutical conformational analysis : issues and methods
Comparability of biotechnological/biological products and biological generics
Application of native electrophoresis for the study of protein conformation
Affinity chromatography including hydrophobic interaction chromatography in the study of biopolymer conformation
Size-exclusion chromatography and bimolecular conformation
Use of analytical ultracentrifugation to study biomolecular conformation
Use of differential scanning calorimetry to measure conformational change in proteins and other biomacromolecules
Light scattering and biomacromolecular conformation
Use of luminescence to measure conformational change in biopharmaceuticals with emphasis on protein and protein drug products
Near-infrared spectroscopy and macromolecular conformation
Use of mid-infrared and Fourier transform infrared spectroscopy to study conformation of biomacromolecules
Use of Raman spectroscopy to evaluate biopharmaceutical conformation
The use of UV-VIS spectrophotometry for the characterization of biopharmaceutical products
Use of optical rotatory dispersion and circular dichroism to study therapeutic biomacromolecule conformation
Use of nuclear magnetic resonance for the characterization of biotherapeutic products
Use of chemical probes for the study of protein conformation
Use of hydrogen exchange in the study of biopharmaceutical conformation
Use of chemical modification for the conformational analysis of biopharmaceuticals
Use of immunology to characterize biopharmaceutical conformation
Use of limited proteolysis to study the conformation of proteins of biotechnological interest
Other technologies for the characterization of conformational change in biopharmaceuticals
Development of an experimental approach for the study of the conformation of a biological therapeutic product.
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Approaches to the conformational analysis of biopharmaceuticals by Roger L. Lundblad. ISBN 9781439807804. Published by CRC Press in 2010. Publication and catalogue information, links to buy online and reader comments.
