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Viral vectors for gene therapy : methods and protocols
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Viral vectors for gene therapy : methods and protocols

Publication Data

Descriptive Notes

"e-ISSN 1940-6029."

Contents

Introduction to viral vectors
Introduction to gene therapy: A clinical aftermath
Host cells and cell banking
Overview of current scalable methods for purification of viral vectors
Methods to construct recombinant adenovirus vectors
Manufacturing of adenovirus vectors: Production and purification of helper dependent adenovirus
Manufacturing of retroviruses
Lentiviral vectors
Adeno-associated viruses
Manufacturing of adeno-associated viruses, for example: AAV2
Vector characterization methods for quality control testing of recombinant adeno-associated viruses
Baculoviruses mediate efficient gene expression in a wide range of vertebrate cells
Herpes simplex virus type 1-derived recombinant and amplicon vectors
Manufacture of measles viruses
In vivo gene delivery into hCD34+ cells in a humanized mouse model
In vivo evaluation of gene transfer into mesenchymal cells (in view of cartilage repair)
Ethical consideration
Clinical trials of GMP products in the gene therapy field.

Topics

Catalogue Data

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Viral vectors for gene therapy : methods and protocols. ISBN 9781617790942. Published by Humana in 2011. Publication and catalogue information, links to buy online and reader comments.

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